Manchester United will be concerned about Raphael Varane’s fitness after he hobbled out against Spain in the UEFA Nations Cup final on Sunday night.
Before halftime, Varane seemed to take a hit after straining to cut off a low cross from Gavi.
He immediately signalled for a substitution and was replaced by Dayot Upamecano.
Varane’s injury will worry United, as he was spotted sitting on the bench with ice strapped to his right quad.
The Red Devils face Leicester City next in the Premier League and manager Ole Gunnar Solskjaer is already without Harry Maguire.
In the center of defense, Solskjaer is likely to select Eric Bailly or Phil Jones to join Victor Lindelof.
Varane has made just seven appearances for United in all competitions since coming from Real Madrid in the summer.
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